Douglas Lauffenburger, MIT
"Multivariate Cue/Signal/Response Analysis of Cell Decision Processes"
Talked about interesting methods for the survey of signal transduction. Looks at temporal (dynamic) activation over short time points using protein abundance as wall as kinase activity all on a chip. They find that different phosphorylation sites are activated at different times. This is done using a novel mass spec labeling method. This means that its site-specific response that matters not the abundance as traditionally assumed. He mentions that the data set is very rich and ripe for data mining using bayesian approaches.