Blogging the biotechnology revolution

Systems Biology is changing the way biology is done. Is it a fad or is it effective? This blog tracks current happenings and helps you stay on top of the field. You can find a list of relevant papers at systems biology paper watch Have you heard a talk or read a paper in bioinformatics / systems biology you would like to tell other people about? Email: and get the word out!

Saturday, December 03, 2005

Eric Davidson, California Institute of Technology (CalTech)
"Functional properties of the gene regulatory network for early sea urchin development"
Uses BioTapestry software to visualize networks
~50 genes with knockout and expression measurements in sea urchin come up with a detailed regulatory network.

looked at network evolution between starfish and sea urchin. the cell differentiation topology is there. the majority of connections in the ~8 gene system they looked at are the same, including loops.
However there are alot of differences making the conservation of that subsystem remarkable.

Suggests the presence of network 'kernels' that drive basal development programs in organisms in this phylum since the cambrian.


Post a Comment

<< Home