Eric Davidson, California Institute of Technology (CalTech)
"Functional properties of the gene regulatory network for early sea urchin development"
Uses BioTapestry software to visualize networks
~50 genes with knockout and expression measurements in sea urchin come up with a detailed regulatory network.

looked at network evolution between starfish and sea urchin. the cell differentiation topology is there. the majority of connections in the ~8 gene system they looked at are the same, including loops.
However there are alot of differences making the conservation of that subsystem remarkable.

Suggests the presence of network 'kernels' that drive basal development programs in organisms in this phylum since the cambrian.