Blogging the biotechnology revolution

Systems Biology is changing the way biology is done. Is it a fad or is it effective? This blog tracks current happenings and helps you stay on top of the field. You can find a list of relevant papers at systems biology paper watch Have you heard a talk or read a paper in bioinformatics / systems biology you would like to tell other people about? Email: and get the word out!

Saturday, December 03, 2005

Mike Levine, UC Berkeley
"Genome regulatory network controlling gastrulation of the Drosophila embryo"
His group found 10 noncoding genes regulated by the dorsal gradient in fly and half are miRNAs.
orientation of the enhancer is important, if you reverse it you see disrupted effects.
Ciona (sea squirt) notochord development network mapped out using a electroporation transgene system
Most of this talk was out of my field but I found it interesting that they found that when they expand the progenitor field of early heart development in sea squirts that instead of a bigger heart, they get a more complex 2-chambered heart. In theory, this supports a mechanism for mutations to function in terms of adding complexity through mutation.


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